Tissue FISH studies
Also known as: Tissue FISH Studies, POC FISH« Back to test list
Abnormalities of chromosome structure or number can cause miscarriage. Chromosome analysis can detect these abnormalities in the products of conception. These abnormalities can provide diagnostic information. If the tissue has been placed in formalin, no analysis through tissue culture is possible, however FISH studies can be used to look for the common trisomies.
Most chromosome abnormalities identified in the products of conception after a spontaneous miscarriage are de novo events that do not carry medical implications for future pregnancies. Chromosome studies of the parents are usually not indicated.
However, parental studies may sometimes be recommended by the laboratory because of specific findings.
Fluorescent in situ hybridisation (FISH) analysis using probes for the common trisomies.
This test can be requested by any medical practitioner.
Paraffin sections of the material to be tested.