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Also known as: t(X;18) FISH

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The t(X;18) translocation results in fusion of the SS18 gene on chromosome 18 with one of three related genes on the short arm of the X. The probe determines breakage of SS18. This test has diagnostic implications.

Clinical Utility

The rearrangement is specific for synovial sarcoma, and occurs in around 80% of these tumours.

This is an assay for non-heritable mutations. It does not raise issues of ethics or consent that are different from most other investigations ordered in the routine care of a patient.



Test Method

Fluorescent in situ hybridisation (FISH) analysis, using probes to detect gene fusions involving the SS18 gene.

Test Ordering

This test is usually requested by an oncologist.

Formalin fixed, paraffin-embedded tissue (FFPE) – 10 sections of 4 uM thickness, dried overnight at 37 degrees onto charged/coated slides.


$355 - $410

The price varies according to the specific clinical conditions for a particular patient. Please contact Sonic Genetics on 1800 010 447 for more information.

Medicare Rebate

This test is not rebated by Medicare. The laboratory assumes that the patient or client has provided informed financial consent for the test.

Turnaround Time

2 working days.

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