Our Tests

Pharmacogenomic Screen (Sonic PGx Panel)

Also known as: Pharmaco Profile, Sonic PGx Panel, Pharmacogenomics Panel

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This test detects clinically important genetic variants that affect drug metabolism. These variants modify the rate at which certain drugs are activated or broken down. This information can be used to predict whether a drug or drug dose is likely to be effective and identify patients at risk of serious or intolerable side-effects. Therefore, this testing has a role in identifying patients who may benefit from modified dosing or avoiding a specific drug.

Clinical Utility

The laboratory report includes the genotype result and metaboliser status for all genes included in the panel, and implications regarding drug choice or dose. Panel-based testing is advantageous because it provides information relevant to both current medications and those that may be prescribed in future.

Additional factors, including illness, nutrition and concurrent medication, can contribute to patient metaboliser status at a given time and should therefore be considered when using the result from this test to determine drug dosage.



Test Method

Mass spectrometry-based targeted detection of single nucleotide variants and copy number variant detection by real-time PCR.

Test Ordering

This test can be requested by any medical practitioner.

4 mL blood in EDTA is preferred. Buccal swabs are available on request, please contact the laboratory if this method of collection is required.

Specimens may be collected by the requesting practitioner or at any Sonic Healthcare pathology collection centre.

To help ensure the quality of the test, a genetic test should be done with a dedicated sample whenever possible, i.e. a sample collected specifically for that test rather than a sample that is used for multiple tests. We also recommend that the patient or another adult check the labelling of request forms and sample tubes.

Special Instructions

Please list current and proposed medications on the request form. Please highlight any medications that have caused problems in the past.