HLA DR and DQ typing may be useful to add weight for the diagnosis of a variety of autoimmune diseases. Associations with disease vary by population background. HLA testing in these disorders is not diagnostic for any one particular disease, and does not exclude a particular disease.
The test report will define the HLA DR and DQ type of the patient.
This is not a diagnostic test and the result does not prove or exclude a specific clinical diagnosis in an affected person.
This is an assay for heritable variants which can alter the probability that a person will develop a disorder. The test result is not, in isolation, diagnostic of a disease and the test result is not necessarily clinically significant for the patient's relatives.
Analysis of the gene sequence of the relevant HLA gene for the presence of specific variants.
Requesting the test
This test can be requested by any medical practitioner.
4 mL blood in EDTA. Specimens may be collected by the requesting practitioner or at any Sonic Healthcare collection centre (see link below).
To help ensure the quality of the test, a genetic test should be done with a dedicated sample whenever possible i.e. a sample collected specifically for that test rather than a sample that is used for multiple tests.
We recommend that the patient or another adult check the labelling of request forms and sample tubes.