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HLA panel screen (DR and DQ)

Also known as: HLA-DR, HLA-DQ

Test category:

Immunology - Autoimmune

Use of test


HLA DR and DQ typing may be useful to add weight for the diagnosis of a variety of autoimmune diseases. Associations with disease vary by population background. HLA testing in these disorders is not diagnostic for any one particular disease, and does not exclude a particular disease.


The test report will define the HLA DR and DQ type of the patient.

This is not a diagnostic test and the result does not prove or exclude a specific clinical diagnosis in an affected person.

Ethical considerations:

This is an assay for heritable variants which can alter the probability that a person will develop a disorder. The test result is not, in isolation, diagnostic of a disease and the test result is not necessarily clinically significant for the patient's relatives.


Analysis of the gene sequence of the relevant HLA gene for the presence of specific variants.

Requesting the test


This test can be requested by any medical practitioner.

Sample required:

4 mL blood in EDTA. Specimens may be collected by the requesting practitioner or at any Sonic Healthcare collection centre (see link below).

To help ensure the quality of the test, a genetic test should be done with a dedicated sample whenever possible i.e. a sample collected specifically for that test rather than a sample that is used for multiple tests.

We recommend that the patient or another adult check the labelling of request forms and sample tubes. 

>Link to Sonic Healthcare collection centres

Special instructions:

Please specify the disorder/s of concern so that the laboratory can provide a useful interpretation.

Turnaround time:

10 business days.


This test has a Medicare rebate which, subject to the requirements of the Medicare descriptor being met, may cover all or part of the cost.


The Medicare details, including descriptor and schedule fee, are listed under MBS item 71151.

Click here for our billing policy.