Sonic Genetics provides a number of gene panels for genetic testing in familial cardiovascular disorders. A panel is defined by the clinical features of a selected cardiovascular disorder or group of disorders in an affected patient. In general, these panels are not suitable for determining the risk of cardiovascular disease in an unaffected person. However, if a mutation in one of the genes on a panel has already been identified in a relative, testing an unaffected family member for that mutation may be clinically warranted.
Each panel is selected from a list of genes on the basis of the clinical presentations associated with the selected genes. Some genes may have multiple presentations and hence are listed in more than one panel.
> Download the panel list
The genes included in the panel list are under continual review. Genes currently included in the non-Medicare rebated tests can be found here..
If further details are required for any gene, https://omim.org/ is a good reference site.
Please note that we have not indicated whether a gene can cause multiple cardiac and non-cardiac disorders; this information is available in the external omim link above. This information may assist doctor and patient in considering the significance of incidental findings arising from a panel test.
Please note that, even if a mutation is identified in a specific gene, an associated non-cardiac disorder is not necessarily likely to occur or to be untreatable.
We provide this supplementary information in good faith, but recognise that our list is not comprehensive; we have included links to further information should this be sought. Clinicians should not rely solely on the summary we have provided.