Our Tests

MYCN FISH

Also known as: N-MYC FISH, 2p23 FISH

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Purpose

The N-MYC (MYCN) oncogene is overexpressed in a number of tumours, such as gliomas, lung and PNET. The test has prognostic implications.

Clinical Utility

N-MYC amplification is particularly useful in neuroblastomas, where it is an indicator of poor prognosis.

This is an assay for non-heritable mutations. It does not raise issues of ethics or consent that are different from most other investigations ordered in the routine care of a patient.

Genes

MYCN

Test Method

Fluorescent in situ hybridisation (FISH) analysis, using probes to enumerate the N-MYC gene.

Test Ordering

This test is usually requested by an oncologist.

Formalin fixed, paraffin-embedded tissue (FFPE) – 10 sections of 4 uM thickness, dried overnight at 37 degrees onto charged/coated slides.

Price

Pricing note:

The price varies according to the specific clinical conditions for a particular patient. Please contact Sonic Genetics on 1800 010 447 for more information.

Medicare Rebate

This test is not rebated by Medicare. The laboratory assumes that the patient or client has provided informed financial consent for the test.

Turnaround Time

2 working days.

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