Our Tests

EGFR Screen

Also known as: EGFR Gene Test

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Purpose

Mutations in the EGFR (epidermal growth factor receptor) gene can guide the choice of therapy in patients with non-small cell lung cancer (NSCLC). Clinically relevant mutations occur in exons 18, 19, 20 and 21 of the gene.

Clinical Utility

The presence of specific EGFR mutations in non-small cell lung cancer (NSCLC) indicates sensitivity or resistance to EGFR tyrosine kinase inhibitor therapies.

This is an assay for non-heritable mutations. It does not raise issues of ethics or consent that are different from most other investigations ordered in the routine care of a patient.

Genes

EGFR

Test Method

The cobas EGFR Mutation Test is used to detect the presence of several different mutations in the EGFR gene.

Test Ordering

This test is usually requested by an oncologist. If ordered by a pathologist, the Medicare rebate may still apply. Please use the specific request form (see link below).

Formalin fixed, paraffin-embedded tissue (FFPE) – 10 sections of 4 uM thickness, dried overnight at 37 degrees onto charged/coated slides.

Special Instructions

Please stain the first section with H&E, and label each slide with patient and block identifiers. Label the unstained sections sequentially (slides 2-10). The request should be accompanied by a completed Somatic Mutation Test Request Form and a copy of the original histopathology report.

Price

$397.35

This test may have a rebate for all or part of the cost.

Medicare Rebate

This test has a Medicare rebate of $337.75, subject to the requirements of the Medicare descriptor being met. The MBS item number is 73337.

Turnaround Time

5-10 working days.