Our Tests

6q21 FISH

Also known as: 6q21 FISH

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Purpose

Deletions affecting the long arm of chromosome 6, including the 6q21 region, are common in mature B-cell lymphoid neoplasms, for example, plasma cell neoplasms, mantle cell lymphoma, and B-cell non-Hodgkin lymphoma, particularly lymphoplasmacytic lymphoma. These deletions can assist in subsequent monitoring of disease.

Clinical Utility

Presence of a 6q21 deletion is not prognostically significant, but can be a marker for quantitative population size estimation.

This is an assay for non-heritable mutations. It does not raise issues of ethics or consent that are different from most other investigations ordered in the routine care of a patient.

Genes

Not specified

Test Method

Fluorescent in situ hybridisation (FISH) analysis, using probes located at 6q21.

Test Ordering

This test is usually requested by a haematologist or oncologist.

0.5 mL bone marrow in transport media, or 5-10 mL blood in lithium heparin.

To help ensure the quality of the test, a genetic test should be done with a dedicated sample whenever possible i.e. a sample collected specifically for that test rather than a sample that is used for multiple tests.

We also recommend that the patient or another adult check the labelling of request forms and sample tubes.

Price

$205 - $255

The price varies according to the specific clinical conditions for a particular patient. Please contact Sonic Genetics on 1800 010 447 for more information.

Medicare Rebate

This test is not rebated by Medicare. The laboratory assumes that the patient or client has provided informed financial consent for the test.

Turnaround Time

2 working days